CLPS antibody
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- Target See all CLPS Antibodies
- CLPS (Colipase, Pancreatic (CLPS))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CLPS antibody is un-conjugated
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Application
- Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CLPS (NP_001823.1).
- Isotype
- IgG
- Top Product
- Discover our top product CLPS Primary Antibody
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- Application Notes
- IF 1:10-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CLPS (Colipase, Pancreatic (CLPS))
- Alternative Name
- CLPS (CLPS Products)
- Synonyms
- CLPS antibody, 2200003J09Rik antibody, COLQ antibody, colipase antibody, colipase, pancreatic antibody, CLPS antibody, Clps antibody
- Background
- The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 12kDa
Calculated_MW: 11kDa
- Gene ID
- 1208
- UniProt
- P04118
- Pathways
- Lipid Metabolism
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