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CLPS antibody

CLPS Reactivity: Human, Mouse IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6570380
  • Target See all CLPS Antibodies
    CLPS (Colipase, Pancreatic (CLPS))
    Reactivity
    • 27
    • 19
    • 17
    • 5
    • 5
    • 3
    Human, Mouse
    Host
    • 50
    • 6
    Rabbit
    Clonality
    • 53
    • 3
    Polyclonal
    Conjugate
    • 23
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLPS antibody is un-conjugated
    Application
    • 25
    • 23
    • 14
    • 14
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CLPS (NP_001823.1).
    Isotype
    IgG
    Top Product
    Discover our top product CLPS Primary Antibody
  • Application Notes
    IF 1:10-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CLPS (Colipase, Pancreatic (CLPS))
    Alternative Name
    CLPS (CLPS Products)
    Synonyms
    CLPS antibody, 2200003J09Rik antibody, COLQ antibody, colipase antibody, colipase, pancreatic antibody, CLPS antibody, Clps antibody
    Background
    The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 12kDa

    Calculated_MW: 11kDa

    Gene ID
    1208
    UniProt
    P04118
    Pathways
    Lipid Metabolism
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