IL11RA antibody

Catalog No. ABIN6570578

Product Details anti-IL11RA Antibody

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL11RA antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human IL11RA

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL11RA

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Alternative Name: IL11RA (IL11RA Products)

Synonyms: CRSDA antibody, fi26e06 antibody, il-11ra antibody, wu:fi26e06 antibody, AI314697 antibody, GP130 antibody, Il-11ra antibody, Il11ra antibody, Il11ra2 antibody, NR1 antibody, interleukin 11 receptor subunit alpha antibody, interleukin 11 receptor, alpha antibody, interleukin 11 receptor subunit alpha 1 antibody, interleukin 11 receptor, alpha chain 1 antibody, IL11RA antibody, il11ra antibody, Il11ra1 antibody, Il11ra antibody

Background:

Synonyms: CRSDA,hCG_2011440,I11RA,IL-11 receptor subunit alpha,IL-11R subunit alpha,IL-11R-alpha,IL-11RA,IL11RA,Interleukin 11 receptor alpha,Interleukin 11 receptor alpha chain,Interleukin-11 receptor subunit alpha,MGC2146

Background: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.

Molecular Weight:

Observed_MW: 45kDa

Calculated_MW: 41kDa/45kDa

Gene ID: 3590

UniProt: Q14626

Pathways: JAK-STAT Signaling, Growth Factor Binding