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NPHP1 antibody

NPHP1 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6570617
  • Target See all NPHP1 Antibodies
    NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
    Reactivity
    • 28
    • 14
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 28
    • 1
    Rabbit
    Clonality
    • 28
    • 1
    Polyclonal
    Conjugate
    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPHP1 antibody is un-conjugated
    Application
    • 18
    • 11
    • 8
    • 5
    • 4
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human NPHP1 (NP_001121651.1).
    Isotype
    IgG
    Top Product
    Discover our top product NPHP1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
    Alternative Name
    NPHP1 (NPHP1 Products)
    Synonyms
    JBTS4 antibody, NPH1 antibody, SLSN1 antibody, nephrocystin-1 antibody, NPHP1 antibody, im:7162391 antibody, wu:fi59g07 antibody, zgc:152930 antibody, Nphp1 antibody, nephrocystin 1 antibody, nephronophthisis 1 (juvenile) homolog (human) antibody, nephronophthisis 1 (juvenile) L homeolog antibody, nephronophthisis 1 antibody, nephrocystin-1 antibody, NPHP1 antibody, Nphp1 antibody, nphp1.L antibody, nphp1 antibody, LOC100725987 antibody
    Background
    This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 80kDa

    Calculated_MW: 69kDa/77kDa/83kDa

    Gene ID
    4867
    UniProt
    O15259
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