PDE5A antibody

Catalog No. ABIN6570728

Product Details anti-PDE5A Antibody

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE5A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human PDE5A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDE5A

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Alternative Name: PDE5A (PDE5A Products)

Synonyms: CGB-PDE antibody, CN5A antibody, PDE5 antibody, PDE5A2 antibody, Cgbpde antibody, Cn5n antibody, Pde5 antibody, Pde5a1 antibody, PDE5A antibody, pde5a antibody, cgb-pde antibody, cn5a antibody, pde5 antibody, pde5a1 antibody, phosphodiesterase 5A antibody, phosphodiesterase 5A, cGMP-specific antibody, phosphodiesterase 5A S homeolog antibody, phosphodiesterase 5A, cGMP-specific, b antibody, PDE5A antibody, Pde5a antibody, pde5a.S antibody, pde5ab antibody, pde5a antibody

Background:

Synonyms: 5''-cyclic phosphodiesterase,CGB PDE,CGB-PDE,CGBPDE,cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase,cGMP binding cGMP specific 35 cyclic nucleotide phosphodiesterase,cGMP binding cGMP specific phosphodiesterase,cGMP binding/cGMP specific phosphodiesterase,cGMP specific 3'5' cyclic phosphodiesterase,cGMP specific phosphodiesterase PDE5A2,cGMP specific phosphodiesterase type 5A,cGMP-binding cGMP-specific phosphodiesterase,cGMP-specific 3'',CN5A,CN5N,PDE 5,PDE 5A,PDE5,Pde5a,PDE5A,PDE5A1,Phosphodiesterase 5A,Phosphodiesterase 5A cGMP specific,Phosphodiesterase isozyme 5

Background: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Molecular Weight:

Observed_MW: 100kDa

Calculated_MW: 94kDa/99kDa

Gene ID: 8654

UniProt: O76074

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling