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PIAS3 antibody

PIAS3 Reactivity: Human, Rat, Mouse IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6570891
  • Target See all PIAS3 Antibodies
    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
    Reactivity
    • 34
    • 19
    • 16
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 31
    • 3
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 27
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIAS3 antibody is un-conjugated
    Application
    • 25
    • 15
    • 12
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PIAS3 (NP_006090.2).
    Isotype
    IgG
    Top Product
    Discover our top product PIAS3 Primary Antibody
  • Application Notes
    IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
    Alternative Name
    PIAS3 (PIAS3 Products)
    Synonyms
    PIAS3 antibody, Pias3l antibody, ZMIZ5 antibody, protein inhibitor of activated STAT 3 antibody, protein inhibitor of activated STAT, 3 antibody, protein inhibitor of activated STAT 3 L homeolog antibody, PIAS3 antibody, pias3 antibody, Pias3 antibody, pias3.L antibody
    Background
    This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.
    Molecular Weight

    Observed_MW: 68kDa

    Calculated_MW: 68kDa

    Gene ID
    10401
    UniProt
    Q9Y6X2
    Pathways
    JAK-STAT Signaling
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