COPS6 antibody

Catalog No. ABIN6570898

Product Details anti-COPS6 Antibody

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS6 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human COPS6 (NP_006824.2).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COPS6

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Alternative Name: COPS6 (COPS6 Products)

Synonyms: CG6932 antibody, CH6 antibody, Csn6 antibody, Dch6 antibody, Dmel\\CG6932 antibody, zgc:112075 antibody, Sgn3 antibody, VIP/MOV34 antibody, CSN6 antibody, MOV34-34KD antibody, COP9 signalosome subunit 6 antibody, COP-9 SigNalosome subunit antibody, COPS6 antibody, Cops6 antibody, CSN6 antibody, cops6 antibody, csn-6 antibody

Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.

Molecular Weight:

Observed_MW: 36kDa

Calculated_MW: 36kDa

Gene ID: 10980

UniProt: Q7L5N1

Pathways: Cell Division Cycle