SIRT3 antibody

Catalog No. ABIN6571049

Product Details anti-SIRT3 Antibody

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: A synthetic peptide of human SIRT3

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Alternative Name: SIRT3 (SIRT3 Products)

Synonyms: zgc:158774 antibody, sirtuin antibody, SIR2L3 antibody, 2310003L23Rik antibody, AI848213 antibody, Sir2l3 antibody, sirtuin 3 antibody, sirt3 antibody, SIRT3 antibody, Sirt3 antibody

Background:

Synonyms: hSIRT 3,hSIRT3,Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase,NAD dependent deacetylase sirtuin 3 mitochondrial,NAD-dependent protein deacetylase sirtuin-3,mitochondrial,Regulatory protein SIR2 homolog 3,Silent mating type information regulation 2 S.cerevisiae homolog 3,Sir 2 like 3,SIR 2 like protein 3,SIR 3,SIR2 L3,Sir2 like 3,SIR2 like protein 3,SIR2-like protein 3,SIR2L3,SIR3,SIRT 3,SIRT3,Sirtuin 3,Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae),Sirtuin type 3,Sirtuin3

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Molecular Weight:

Observed_MW: 44kDa, 27kDa

Calculated_MW: 28kDa/43kDa

Gene ID: 23410

UniProt: Q9NTG7