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Topoisomerase I antibody

TOP1 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6571324
  • Target See all Topoisomerase I (TOP1) Antibodies
    Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
    Reactivity
    • 66
    • 25
    • 14
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 54
    • 10
    • 2
    Rabbit
    Clonality
    • 44
    • 22
    Polyclonal
    Conjugate
    • 36
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Topoisomerase I antibody is un-conjugated
    Application
    • 42
    • 20
    • 20
    • 14
    • 9
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human TOP1 (NP_003277.1).
    Isotype
    IgG
    Top Product
    Discover our top product TOP1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
    Alternative Name
    TOP1 (TOP1 Products)
    Synonyms
    CG6146 antibody, Dmel\\CG6146 antibody, TOP1 antibody, TopI antibody, Topo I antibody, TopoI antibody, dTopoI antibody, l(1)G0134 antibody, l(1)G0201 antibody, l(1)G0229 antibody, l(1)G0278 antibody, l(1)top1 antibody, top1 antibody, topo I antibody, topoI antibody, DNA topoisomerase 1 beta antibody, DNA topoisomerase I alpha antibody, MGO1 antibody, MGOUN 1 antibody, MTE17.1 antibody, MTE17_1 antibody, TOP1BETA antibody, TOPOISOMERASE 1 antibody, TOPI antibody, AI467334 antibody, D130064I21Rik antibody, Top-1 antibody, Ab2-086 antibody, topi antibody, Topoisomerase 1 antibody, DNA topoisomerase I antibody, DNA topoisomerase I alpha antibody, DNA topoisomerase 1 antibody, topoisomerase (DNA) I antibody, DNA topoisomerase I, gene 1 L homeolog antibody, Top1 antibody, top1 antibody, topA antibody, ZMO1193 antibody, MRAD2831_RS63095 antibody, Lferr_0016 antibody, PC1_2015 antibody, Za10_0136 antibody, Gbro_0575 antibody, Dd586_2108 antibody, Kvar_3044 antibody, Alvin_2069 antibody, Dacet_0849 antibody, Mrub_1615 antibody, Arnit_2962 antibody, Ndas_4953 antibody, Trad_2377 antibody, Acear_1653 antibody, Mahau_0844 antibody, Mesop_4109 antibody, Thein_1586 antibody, Theth_0241 antibody, TOP1ALPHA antibody, top-1 antibody, TOP1 antibody, top1.1.L antibody
    Target Type
    Viral Protein
    Background
    This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
    Molecular Weight

    Observed_MW: 108kDa

    Calculated_MW: 90kDa

    Gene ID
    7150
    UniProt
    P11387
    Pathways
    Caspase Cascade in Apoptosis, Stem Cell Maintenance
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