Cadherin-16 antibody

Catalog No. ABIN6571429

Product Details anti-Cadherin-16 Antibody

Target: Cadherin-16 (CDH16)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CDH16 (NP_004053.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: CDH16 (CDH16 Products)

Synonyms: cadherin 16 antibody, CDH16 antibody, Cdh16 antibody

Background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Molecular Weight:

Observed_MW: 110kDa

Calculated_MW: 79kDa/85kDa/87kDa/89kDa

Gene ID: 1014

UniProt: O75309