MRPL12 antibody

Catalog No. ABIN6571670

Product Details anti-MRPL12 Antibody

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL12 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human MRPL12 (NP_002940.2).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MRPL12

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Alternative Name: MRPL12 (MRPL12 Products)

Synonyms: 5c5-2 antibody, L12mt antibody, MRP-L31/34 antibody, MRPL7 antibody, MRPL7/L12 antibody, RPML12 antibody, GB14723 antibody, MRPL12 antibody, 0610034O11Rik antibody, 1500031N16Rik antibody, MRP-L12 antibody, Rpml12 antibody, Rpm12 antibody, im:6893415 antibody, zgc:112445 antibody, mrpl12 antibody, mitochondrial ribosomal protein L12 antibody, 39S ribosomal protein L12, mitochondrial antibody, mitochondrial nucleoid protein antibody, mitochondrial ribosomal protein L12 L homeolog antibody, MRPL12 antibody, LOC409926 antibody, CAALFM_C207190CA antibody, Mrpl12 antibody, mrpl12 antibody, mrpl12.L antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.

Molecular Weight:

Observed_MW: 21kDa

Calculated_MW: 21kDa

Gene ID: 6182

UniProt: P52815