FAM65B antibody

Catalog No. ABIN6571960

Product Details anti-FAM65B Antibody

Target: FAM65B (Family with Sequence Similarity 65, Member B (FAM65B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM65B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant Protein of human FAM65B

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FAM65B

Target: FAM65B (Family with Sequence Similarity 65, Member B (FAM65B))

Alternative Name: FAM65B (FAM65B Products)

Synonyms: C6orf32 antibody, DIFF40 antibody, DIFF48 antibody, MYONAP antibody, PL48 antibody, 1700108N18Rik antibody, 6330500D04Rik antibody, AI225904 antibody, E430013J17Rik antibody, si:dkey-218n20.1 antibody, Ab2-162 antibody, RGD1306939 antibody, RHO family interacting cell polarization regulator 2 antibody, family with sequence similarity 65, member B antibody, ripor2 antibody, RIPOR2 antibody, Ripor2 antibody, FAM65B antibody

Background:

Synonyms: RHO Family Interacting Cell Polarization Regulator 2,Family With Sequence Similarity 65 Member B,C6orf32,FAM65B,DIFF48,PL48,Myogenesis-Related And NCAM-Associated Protein Homolog,Rho Family-Interacting Cell Polarization Regulator 2,Family With Sequence Similarity 65, Member B,Chromosome 6 Open Reading Frame 32,Protein FAM65B,KIAA0386,DFNB104,DIFF40,MYONAP

Background: This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients.

Molecular Weight:

Observed_MW: 118kDa

Calculated_MW: 65kDa/118kDa

Gene ID: 9750

UniProt: Q9Y4F9

Pathways: Transition Metal Ion Homeostasis