CD103 antibody

Catalog No. ABIN6572079

Product Details anti-CD103 Antibody

Target: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD103 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ITGAE

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD103

Target: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Alternative Name: ITGAE (ITGAE Products)

Synonyms: A530055J10 antibody, CD103 antibody, aM290 antibody, alpha-E1 antibody, alpha-M290 antibody, HUMINAE antibody, integrin alpha E, epithelial-associated antibody, integrin subunit alpha E antibody, Itgae antibody, ITGAE antibody

Background:

Synonyms: A530055J10,alpha-E1,alpha-M290,aM290,Antigen CD103,CD 103,CD103,CD103 antigen,HML 1 antigen,HML-1 antigen,HML1 antigen,Human mucosal lymphocyte antigen 1,Human mucosal lymphocyte antigen 1,alpha subunit,Huminae,Integrin alpha E heavy chain,Integrin alpha E light chain,Integrin alpha E,epithelial-associated,Integrin alpha E1,Integrin alpha IEL,Integrin alpha M290,Integrin alpha-E heavy chain,Integrin alpha-IEL,Integrin,alpha E (antigen CD103,human mucosal lymphocyte antigen 1,alpha polypeptide),Integrin,alpha E,ITAE,Itgae,MGC141996,MGC183601,Mucosal lymphocyte 1 antigen,Mucosal lymphocyte antigen 1

Background: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

Molecular Weight:

Observed_MW: 110kDa

Calculated_MW: 130kDa

Gene ID: 3682

UniProt: P38570