CACNA2D2 antibody (AA 643-671)

Catalog No. ABIN657303

Product Details anti-CACNA2D2 Antibody

Target: CACNA2D2 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2))

Binding Specificity: AA 643-671

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA2D2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CACNA2D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 643-671 amino acids from the Central region of human CACNA2D2.

Clone: RB32703

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CACNA2D2

Target: CACNA2D2 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2))

Alternative Name: CACNA2D2 (CACNA2D2 Products)

Synonyms: CACNA2D antibody, LUAC11.1 antibody, Cacna2d antibody, a2d2 antibody, du antibody, mKIAA0558 antibody, td antibody, torpid antibody, calcium voltage-gated channel auxiliary subunit alpha2delta 2 antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 2 antibody, CACNA2D2 antibody, Cacna2d2 antibody

Background: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

Molecular Weight: 129817

Gene ID: 9254

NCBI Accession: NP_001005505, NP_001167522, NP_006021

UniProt: Q9NY47

Pathways: Skeletal Muscle Fiber Development