ARHGDIB antibody (C-Term)

Catalog No. ABIN657665

Product Details anti-ARHGDIB Antibody

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Binding Specificity: AA 160-188, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGDIB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human ARHGDIB.

Clone: RB33730

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ARHGDIB Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-ARHGDIB antibody (ABIN657665)

Huang, Zhang, Jiang, Chen, Liu, Ge, Li, Dang, Wen, Liu, Lu, Tang: "RhoGDI? Inhibits Bone Morphogenetic Protein 4 (BMP4)-induced Adipocyte Lineage Commitment and Favors Smooth Muscle-like Cell Differentiation." in: The Journal of biological chemistry, Vol. 290, Issue 17, pp. 11119-29, (2015) (PubMed).

Target Details for ARHGDIB

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Alternative Name: ARHGDIB (ARHGDIB Products)

Synonyms: ARHGDIB antibody, zgc:65966 antibody, arhgdib antibody, MGC69067 antibody, gdia2 antibody, rhodgi-2 antibody, rhodgi2 antibody, D4 antibody, GDIA2 antibody, GDID4 antibody, LYGDI antibody, Ly-GDI antibody, RAP1GN1 antibody, RhoGDI2 antibody, Gdid4 antibody, Rho GDP dissociation inhibitor (GDI) gamma antibody, Rho GDP dissociation inhibitor (GDI) beta S homeolog antibody, Rho GDP dissociation inhibitor beta antibody, Rho GDP dissociation inhibitor (GDI) beta antibody, Rho, GDP dissociation inhibitor (GDI) beta antibody, arhgdig antibody, arhgdib.S antibody, ARHGDIB antibody, arhgdib antibody, Arhgdib antibody

Background: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).

Molecular Weight: 22988

Gene ID: 397

NCBI Accession: NP_001166

UniProt: P52566

Pathways: Caspase Cascade in Apoptosis