Melanoma gp100 antibody (AA 412-440)

Catalog No. ABIN657675

Product Details anti-Melanoma gp100 Antibody

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Binding Specificity: AA 412-440

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melanoma gp100 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SILV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 412-440 amino acids from the Central region of human SILV.

Clone: RB33755

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SILV Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for Melanoma gp100

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Alternative Name: SILV (PMEL Products)

Background: SILV plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Molecular Weight: 70255

Gene ID: 6490

NCBI Accession: NP_001186982, NP_001186983, NP_008859

UniProt: P40967