SLC11A2 antibody (AA 262-291)

Catalog No. ABIN657723

Product Details anti-SLC11A2 Antibody

Target: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Binding Specificity: AA 262-291

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC11A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SLC11A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-291 amino acids from the Central region of human SLC11A2.

Clone: RB34426

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-SLC11A2 antibody (ABIN657723)

Mondal, Schilling, Folger, Steibel, Buchnick, Zalman, Ireland, Meidan, Smith: "Deciphering the luteal transcriptome: potential mechanisms mediating stage-specific luteolytic response of the corpus luteum to prostaglandin F??." in: Physiological genomics, Vol. 43, Issue 8, pp. 447-56, (2011) (PubMed).

Ramachandran, Tran, Klebba-Faerber, Kardinal, Whetton, Tamura: "An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5." in: RNA (New York, N.Y.), Vol. 17, Issue 11, pp. 1957-66, (2011) (PubMed).

Target Details for SLC11A2

Target: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Alternative Name: SLC11A2 (SLC11A2 Products)

Synonyms: DCT1 antibody, DMT1 antibody, NRAMP2 antibody, Nramp2 antibody, mk antibody, van antibody, Dmt1 antibody, ATNRAMP2 antibody, F8G22.4 antibody, F8G22_4 antibody, NRAMP metal ion transporter 2 antibody, dct1 antibody, dmt1 antibody, nramp2 antibody, SLC11A2 antibody, cb426 antibody, fa07b10 antibody, wu:fa07b10 antibody, zgc:136699 antibody, solute carrier family 11 member 2 antibody, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 antibody, NRAMP metal ion transporter 2 antibody, manganese transport protein antibody, metal transporter Nramp2 antibody, solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 antibody, SLC11A2 antibody, Slc11a2 antibody, NRAMP2 antibody, LOC9327403 antibody, slc11a2 antibody

Background: This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 62266

Gene ID: 4891

NCBI Accession: NP_000608, NP_001167596, NP_001167597, NP_001167598, NP_001167599, NP_001167600, NP_001167601

UniProt: P49281

Pathways: Transition Metal Ion Homeostasis, Proton Transport, Positive Regulation of Endopeptidase Activity