SIRT6 antibody (C-Term)
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- Target See all SIRT6 Antibodies
- SIRT6 (Sirtuin 6 (SIRT6))
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Binding Specificity
- AA 276-305, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIRT6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SIRT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of human SIRT6.
- Clone
- RB34031
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SIRT6 Primary Antibody
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anti-Sirtuin 6 (SIRT6) (AA 1-334) antibody
SIRT6 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 Reactivity: Human WB, ELISA, IHC, ICC, FACS Host: Mouse Monoclonal 2G1H1 unconjugated
anti-Sirtuin 6 (SIRT6) antibodySIRT6 Reactivity: Human, Mouse, Rat, Monkey WB, IP, IF Host: Mouse Monoclonal 6C9-D10-D3 unconjugated
anti-Sirtuin 6 (SIRT6) (AA 290-319), (C-Term) antibodySIRT6 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB2109 unconjugated
anti-Sirtuin 6 (SIRT6) (N-Term) antibodySIRT6 Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (Middle Region) antibodySIRT6 Reactivity: Human, Rat, Dog, Cow WB, IP, ChIP Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 35-274) antibodySIRT6 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 56-105) antibodySIRT6 Reactivity: Human, Mouse, Dog, Monkey, Pig, Bat, Hamster WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 Reactivity: Human ELISA Host: Mouse Monoclonal 1D8 unconjugated
anti-Sirtuin 6 (SIRT6) (C-Term) antibodySIRT6 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- SIRT6 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Expiry Date
- 6 months
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- Target
- SIRT6 (Sirtuin 6 (SIRT6))
- Alternative Name
- SIRT6 (SIRT6 Products)
- Synonyms
- 2810449N18Rik antibody, AI043036 antibody, Sir2l6 antibody, SIR2L6 antibody, zgc:86729 antibody, sirtuin 6 antibody, sirtuin 6 S homeolog antibody, Sirt6 antibody, SIRT6 antibody, sirt6.S antibody, sirt6 antibody
- Background
- NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein (By similarity).
- Molecular Weight
- 39119
- Gene ID
- 51548
- NCBI Accession
- NP_001180214, NP_057623
- UniProt
- Q8N6T7
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