RHOC antibody (C-Term)
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- Target See all RHOC Antibodies
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
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Binding Specificity
- AA 102-130, C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RHOC antibody is un-conjugated
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Application
- Western Blotting (WB)
- Predicted Reactivity
- B
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This RHOC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human RHOC.
- Clone
- RB33831
- Isotype
- Ig Fraction
- Top Product
- Discover our top product RHOC Primary Antibody
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- Application Notes
- WB: 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- RHOC Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Expiry Date
- 6 months
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- Target
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
- Alternative Name
- RHOC (RHOC Products)
- Synonyms
- ARHC antibody, LOC100221682 antibody, ARH9 antibody, H9 antibody, RHOH9 antibody, AI324259 antibody, Arh9 antibody, Arhc antibody, CRHOC antibody, ras homolog family member C L homeolog antibody, ras homolog family member C antibody, rhoc.L antibody, RHOC antibody, rhoc antibody, Rhoc antibody
- Background
- This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- Molecular Weight
- 22006
- Gene ID
- 389
- NCBI Accession
- NP_001036143, NP_001036144, NP_786886
- UniProt
- P08134
- Pathways
- WNT Signaling, Cell-Cell Junction Organization
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