Transglutaminase 2 antibody

Catalog No. ABIN659099

Product Details anti-Transglutaminase 2 Antibody

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transglutaminase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This TGM2 monoclonal antibody is generated from mouse immunized with TGM2 recombinant protein.

Clone: 207CT39-5-5

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Transglutaminase 2

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Alternative Name: TGM2 (TGM2 Products)

Synonyms: G-ALPHA-h antibody, GNAH antibody, TG2 antibody, TGC antibody, tgm2 antibody, zgc:101081 antibody, TgaseII antibody, TGM2 antibody, fc12b04 antibody, wu:fc12b04 antibody, zgc:136700 antibody, TGL2 antibody, G[a]h antibody, TGase2 antibody, tTG antibody, tTGas antibody, transglutaminase 2 antibody, transglutaminase 2, C polypeptide A antibody, transglutaminase 2b antibody, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) antibody, transglutaminase 2, C polypeptide antibody, TGM2 antibody, tgm2a antibody, Tgm2 antibody, tgm2b antibody

Background: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 77329

Gene ID: 7052

NCBI Accession: NP_004604, NP_945189

UniProt: P21980

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling