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Histone H3.1 antibody (Ser10)

HIST1H3B Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN197332
  • Target See all Histone H3.1 (HIST1H3B) Antibodies
    Histone H3.1 (HIST1H3B)
    Binding Specificity
    • 15
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser10
    Reactivity
    • 42
    • 17
    • 17
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 39
    • 3
    • 2
    Rabbit
    Clonality
    • 39
    • 5
    Polyclonal
    Conjugate
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Histone H3.1 antibody is un-conjugated
    Application
    • 31
    • 25
    • 24
    • 16
    • 15
    • 8
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Specificity
    This antibody detects endogenous levels of total Histone H3.1 protein.
    Purification
    Immunoaffinity Chromatography using epitope-specific immunogen.
    Immunogen
    The antiserum was produced against synthesized non-phosphopeptide derived from human Histone H3.1 around the phosphorylation site of Serine 10 (R-K-Sp-T-G).
    Top Product
    Discover our top product HIST1H3B Primary Antibody
  • Application Notes
    Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    Histone H3.1 (HIST1H3B)
    Alternative Name
    Histone H3.1 (HIST1H3B Products)
    Synonyms
    H3 histone antibody, Hist1h2ai antibody, histone cluster 1, H2ai-like1 antibody, histone H3.1 antibody, Hht21p antibody, Hist1h2ail1 antibody, H3.1 antibody, HHT21 antibody
    Background
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fibre is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. Covalent modifications of the canonical core histones, including acetylation, phosphorylation, methylation, and monoubiquitination are used to mark nucleosomes to create chromatin domains with a range of functions. The information encoded by histone modifications can contribute to the formation and/or maintenance of transcriptionally active and inactive chromatin in response to various signalling pathways.Synonyms: H3/a, H3/b, H3/c, H3/d, H3/f, H3/h, H3/i, H3/j, H3/k, H3/l, H3FA, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
    Gene ID
    8350
    NCBI Accession
    NP_003520
    UniProt
    P68431
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