RP2 antibody (AA 244-348)

Catalog No. ABIN6654138

Product Details anti-RP2 Antibody

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Binding Specificity: AA 244-348

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: Amino acids D244-M348 from the human protein were used as the immunogen for the RP2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RP2 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the RP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for RP2

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Alternative Name: RP2 / XRP2 (RP2 Products)

Synonyms: Rp2h antibody, RGD1565124 antibody, RP2 antibody, wu:fj10e02 antibody, wu:fm72d05 antibody, zfrp2 antibody, zgc:55632 antibody, DELXp11.3 antibody, NM23-H10 antibody, NME10 antibody, TBCCD2 antibody, XRP2 antibody, AI662636 antibody, Rp2 antibody, RP2, ARL3 GTPase activating protein antibody, XRP2 protein antibody, XRP2-like protein antibody, retinitis pigmentosa 2 (X-linked recessive) antibody, RP2, ARL3 GTPase activating protein S homeolog antibody, retinitis pigmentosa 2 homolog antibody, Rp2 antibody, RP2 antibody, Bm1_36735 antibody, PITG_13367 antibody, LOAG_11813 antibody, rp2 antibody, rp2.S antibody

Background: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death. The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process