Solute Carrier Family 39 (Zinc Transporter), Member 13 (SLC39A13) (N-Term) antibody

Details for Product No. ABIN6655608
Antigen
Epitope
N-Term
6
4
2
2
1
1
1
Reactivity
Human
15
12
Host
Rabbit
22
5
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
Application
ELISA, Fluorescence Microscopy (FM), Immunohistochemistry (IHC), Western Blotting (WB)
20
19
5
2
1
Options
Immunogen

Immunogen: Anti-ZIP13 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the N-terminus of human ZIP13.

Immunogen Type: Peptide

Isotype IgG
Purification Anti-ZIP13 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of ZIP13 are known to exist, this antibody will detect both isoforms. ZIP13 antibody is predicted to not cross-react with other ZIP family members.
Antigen
Alternative Name ZIP13 (SLC39A13 Antibody Abstract)
Background

Synonyms: ZIP13 Antibody, ZIP13, Zinc transporter ZIP13, LIV-1 subfamily of ZIP zinc transporter 9, LZT-Hs9

Background: The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.

Gene Name: Slc39a13

Gene ID 83637
UniProt Q8NF64
Pathways Transition Metal Ion Homeostasis
Application Notes

Immunohistochemistry Dilution: 2.5 μg/mL

Application Note: Anti-ZIP13 Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 39 kDa in Western Blots of specific cell lysates and tissues.

ELISA Dilution: 1:10,000-1:20,000

Western Blot Dilution: 1-2 μg/mL

IF Microscopy Dilution: 20 μg/mL

Restrictions For Research Use only
Format Liquid
Buffer

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage RT,4 °C,-20 °C
Storage Comment Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.