NLRC5 antibody (NLR Family, CARD Domain Containing 5) (N-Term) Primary Antibody
- Binding Specificity
- This NLRC5 antibody is un-conjugated
- ELISA, Fluorescence Microscopy (FM), Western Blotting (WB)
- Human, Mouse (Murine)
- Cross-Reactivity (Details)
- Cross reactivity with NOD4 from other sources has not been determined.
- Anti-NOD4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography.
Immunogen: Anti-NOD4 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the N-terminus of human NOD4.
Immunogen Type: Peptide
- Application Notes
Application Note: Anti-NOD4 Antibody has been tested for use in ELISA, Western Blotting, Immunocytochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 205 kDa in Western Blots of specific cell lysates and tissues.
ELISA Dilution: 1:10,000
Western Blot Dilution: 1 μg/mL
IF Microscopy Dilution: 20 μg/mL
- For Research Use only
Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- RT,4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Alternative Name
- NOD4 (NLRC5 Antibody Abstract)
- NOD4, CLR16.1, NOD27, AI451557, AK220210, NLR family CARD domain containing 5, NLR family, CARD domain containing 5, NLRC5, nlrc5, Nlrc5
Synonyms: NOD4 Antibody, NOD4, NOD27, CLR16.1, NOD4, Protein NLRC5, Nucleotide-binding oligomerization domain protein 27
Background: NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-kB and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.
Gene Name: NLRC5
- Gene ID
- NCBI Accession