Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CAZIP antibody (Microtubule-associated Tumor Suppressor Candidate 2) (C-Term) Primary Antibody

MTUS2 Reactivity: Human ELISA, FM, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6656002
$411.00
Plus shipping costs $45.00 and $22.00 dry ice
100 μg
local_shipping Shipping to: United States
Delivery in 1 to 2 Business Days
  • Target See all CAZIP (MTUS2) Antibodies
    CAZIP (MTUS2)
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 9
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 7
    • 2
    Rabbit
    Clonality
    • 9
    Polyclonal
    Application
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Fluorescence Microscopy (FM), Immunohistochemistry (IHC), Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse (Murine)
    Cross-Reactivity (Details)
    Cross reactivity with CAZIP from other sources has not been determined.
    Purification
    Anti-CAZIP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography.
    Immunogen

    Immunogen: Anti-CAZIP antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the C-terminus of human CAZIP.

    Immunogen Type: Peptide

    Isotype
    IgG
  • Application Notes

    Immunohistochemistry Dilution: 5 μg/mL

    Application Note: Anti-CAZIP Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 150 kDa in Western Blots of specific cell lysates and tissues.

    ELISA Dilution: 1:5000-1:10000

    Western Blot Dilution: 0.5-1 μg/mL

    IF Microscopy Dilution: 20 μg/mL

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    RT,4 °C,-20 °C
    Storage Comment
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Target
    CAZIP (MTUS2)
    Alternative Name
    CAZIP (MTUS2 Products)
    Synonyms
    KIAA0774, DKFZp468L0812, CAZIP, ICIS, TIP150, 5730592G18Rik, A730013O20Rik, AU067634, C130038G02Rik, Cazip, Gm763, mKIAA0774, microtubule associated tumor suppressor candidate 2, microtubule associated scaffold protein 2, MTUS2, Mtus2
    Background

    Synonyms: CAZIP Antibody, ICIS, CAZIP, TIP150, KIAA0774, Microtubule-associated tumor suppressor candidate 2, Cardiac zipper protein, Tracking protein of 150 kDa

    Background: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.

    Gene Name: MTUS2

    Gene ID
    23281
    NCBI Accession
    NP_001028774
    UniProt
    Q5JR59
You are here:
help Support