Yippee-Like 3 (Drosophila) (YPEL3) (N-Term) antibody Primary Antibody
- Binding Specificity
- ELISA, Fluorescence Microscopy (FM), Western Blotting (WB)
- Human, Mouse (Murine), Rat (Rattus)
- Cross-Reactivity (Details)
- Cross reactivity with YPEL3 from other sources has not been determined.
- Anti-YPEL3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography.
Immunogen: Anti-YPEL3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human YPEL3.
Immunogen Type: Peptide
- Application Notes
Application Note: Anti-YPEL3 Antibody has been tested for use in ELISA, Western Blotting, Immunocytochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 14 kDa in Western Blots of specific cell lysates and tissues.
ELISA Dilution: 1:10,000
Western Blot Dilution: 1 μg/mL
IF Microscopy Dilution: 2.5 μg/mL
Other Performance Data: Immunocytochemistry: 2.5 μg/mL
- For Research Use only
Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- RT,4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Alternative Name
- YPEL3 (YPEL3 Antibody Abstract)
- 0610043B10Rik, 1190001G19Rik, Suap, RGD1564579, yippee-like 3 (Drosophila), yippee like 3, yippee-like 3, Ypel3, YPEL3
Synonyms: YPEL3 Antibody, Protein yippee-like 3
Background: YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
Gene Name: YPEL3
- Gene ID