Retinoid X Receptor gamma antibody

Catalog No. ABIN6657359

Product Details anti-Retinoid X Receptor gamma Antibody

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoid X Receptor gamma antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat (Rattus)

Cross-Reactivity (Details): Cross reactivity to other sources has not been tested.

Purification: Anti-Retinoic Acid Receptor gamma antibody detects Retinoic Acid Receptor gamma. Retinoic Acid Receptor gamma antibody was Protein G purified. This antibody is directed against human retinoic acid receptor gamma protein. Reactivity is expected from the following species based on 100% sequence homology: bovine, mouse, non-human primate and rat.

Immunogen:

Immunogen: Anti-Retinoic Acid Receptor gamma was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the hinged region of RAR-gamma.

Immunogen Type: Peptide

Clone: 1373

Isotype: IgG1

Application Details

Application Notes:

Application Note: Anti-Retinoid X Receptor gamma antibody is suitable for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to the RXR-γ isotype in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Target Details for Retinoid X Receptor gamma

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Alternative Name: Retinoid X Receptor gamma (RXRG Products)

Synonyms: NR2B3 antibody, RXRC antibody, zgc:92183 antibody, RXRgamma antibody, RXRG antibody, RXR-gamma antibody, nr2b3 antibody, xrxrg antibody, rxrc antibody, Nr2b3 antibody, NR2B1 antibody, RXR antibody, rxra antibody, rxrg antibody, retinoid X receptor gamma antibody, retinoid X receptor, gamma b antibody, retinoid X receptor gamma L homeolog antibody, retinoid x receptor, gamma a antibody, RXRG antibody, rxrgb antibody, rxrg.L antibody, rxrg antibody, Rxrg antibody, RXRGAMMA antibody, rxrga antibody

Background:

Synonyms: mouse anti-Retinoid X Receptor gamma Antibody, mouse anti-RXRG antibody, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma

Background: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Gene Name: RXRG

Gene ID: 6258

UniProt: P48443

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway