Cytochrome P450 antibody

Catalog No. ABIN6657370

Product Details anti-Cytochrome P450 Antibody

Target: Cytochrome P450 (CYP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytochrome P450 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Fluorescence Microscopy (FM)

Cross-Reactivity: Human, Rat (Rattus)

Purification: This affinity purified antibody is directed against human cytochrome p450. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis the immunogen sequence shows 83.3% identity with mouse, rat, hamster, and monkey.

Immunogen:

Immunogen: Anti-Cytochrome p450 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human cytochrome p450 conjugated to Keyhole Limpet Hemocyanin (KLH).

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry Dilution: 1:100 - 1:200

Application Note: Anti-Cytochrome p450 has been tested in Western Blot, Immunofluorescence and Immunohistochemistry. Expect a band at ~58kda in western blot using appropriate lysates. Positive controls used include an overexpressing lysate and PC-12 at 1 μg/mL for WB, human kidney and/or lung for IHC, HepG2 for IF at 15 μg/mL.

ELISA Dilution: 5 μg/mL

Western Blot Dilution: 1:1000

IF Microscopy Dilution: 15 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Target Details for Cytochrome P450

Target: Cytochrome P450 (CYP)

Alternative Name: CYTOCHROME p450 (CYP Products)

Synonyms: CPF3 antibody, CYP4F antibody, LTB4H antibody, 6t1 antibody, CG1644 antibody, DmelCG1644 antibody, CYTOCHROME P450 antibody, FAMILY 705 antibody, POLYPEPTIDE 9 antibody, SUBFAMILY A antibody, T20P8.6 antibody, T20P8_6 antibody, cytochrome P450 antibody, family 71 antibody, polypeptide 13 antibody, subfamily A antibody, T11J7.16 antibody, T11J7_16 antibody, F13P17.22 antibody, family 710 antibody, polypeptide 2 antibody, CYP77A7 antibody, FAMILY 77 antibody, POLYPEPTIDE 7 antibody, UNE9 antibody, UNFERTILIZED EMBRYO SAC 9 antibody, POLYPEPTIDE 15 antibody, POLYPEPTIDE 18 antibody, T9E8.50 antibody, T9E8_50 antibody, polypeptide 20 antibody, DL3710C antibody, FCAALL.270 antibody, POLYPEPTIDE 1 antibody, CABBAGE 3 antibody, CBB3 antibody, CONSTITUTIVE PHOTOMORPHOGENIC DWARF antibody, CYP90 antibody, CYP90A antibody, CYP90A1 antibody, CYTOCHROME P450 90A1 antibody, CYTOCHROME P450 MONOOXYGENASE antibody, DWARF 3 antibody, DWF3 antibody, MJJ3.9 antibody, MJJ3_9 antibody, F25C20.24 antibody, F25C20_24 antibody, polypeptide 18 antibody, F22L4.14 antibody, F22L4_14 antibody, FAMILY 86 antibody, POLYPEPTIDE 4 antibody, F13D4.120 antibody, F13D4_120 antibody, family 82 antibody, polypeptide 1 antibody, subfamily F antibody, family 711 antibody, MAX1 antibody, MORE AXILLARY BRANCHES 1 antibody, T1D16.19 antibody, T1D16_19 antibody, F15K20.21 antibody, F15K20_21 antibody, family 94 antibody, subfamily C antibody, F13P17.35 antibody, family 98 antibody, polypeptide 3 antibody, T20B5.9 antibody, T20B5_9 antibody, family 712 antibody, T24P15.16 antibody, T24P15_16 antibody, family 704 antibody, T13E15.10 antibody, F17K2.4 antibody, F4I18.5 antibody, family 86 antibody, LACERATA antibody, LCR antibody, polypeptide 8 antibody, F14M4.22 antibody, family 709 antibody, subfamily B antibody, F14M4.21 antibody, family 87 antibody, polypeptide 9 antibody, T21P5.11 antibody, T21P5_11 antibody, F1C9.32 antibody, F1C9_32 antibody, POLYPEPTIDE 22 antibody, family 705 antibody, polypeptide 23 antibody, polypeptide 30 antibody, subfamily G antibody, family 76 antibody, subfamily D antibody, family 706 antibody, polypeptide 4 antibody, T4C9.140 antibody, T4C9_140 antibody, F18A5.160 antibody, F18A5_160 antibody, family 83 antibody, REDUCED EPIDERMAL FLUORESCENCE 2 antibody, REF2 antibody, DL3695C antibody, family 702 antibody, FCAALL.257 antibody, DL3700W antibody, FCAALL.266 antibody, DL3720W antibody, FCAALL.274 antibody, DL3725W antibody, FCAALL.277 antibody, 21-OH antibody, 21OH antibody, 21OHA antibody, 21OHB antibody, CYP21OH-A antibody, Cyp21 antibody, Cyp21-ps1 antibody, Cyp21B antibody, Cyp21a2-ps antibody, Cyp21a2ps antibody, Oh21-1 antibody, Oh21-2 antibody, CYPIID25 antibody, Cypiiia15 antibody, cytochrome P450 family 4 subfamily F member 3 antibody, CG1644 gene product from transcript CG1644-RA antibody, cytochrome P450, family 705, subfamily A, polypeptide 9 antibody, cytochrome P450 family 71 polypeptide antibody, cytochrome P450, family 710, subfamily A, polypeptide 2 antibody, Cytochrome P450 superfamily protein antibody, cytochrome P450, family 705, subfamily A, polypeptide 15 antibody, cytochrome P450, family 705, subfamily A, polypeptide 18 antibody, cytochrome P450, family 71, subfamily A, polypeptide 20 antibody, cytochrome P450, family 705, subfamily A, polypeptide 1 antibody, cytochrome P450, family 71, subfamily A, polypeptide 18 antibody, cytochrome P450, family 86, subfamily A, polypeptide 4 antibody, cytochrome P450, family 82, subfamily F, polypeptide 1 antibody, cytochrome P450, family 711, subfamily A, polypeptide 1 antibody, cytochrome P450, family 94, subfamily C, polypeptide 1 antibody, cytochrome P450, family 710, subfamily A, polypeptide 1 antibody, cytochrome P450, family 98, subfamily A, polypeptide 3 antibody, cytochrome P450, family 712, subfamily A, polypeptide 1 antibody, cytochrome P450, family 704, subfamily A, polypeptide 1 antibody, cytochrome P450, family 704, subfamily A, polypeptide 2 antibody, cytochrome P450, family 86, subfamily A, polypeptide 8 antibody, cytochrome P450, family 709, subfamily B, polypeptide 2 antibody, cytochrome P450, family 709, subfamily B, polypeptide 1 antibody, cytochrome P450, family 87, subfamily A, polypeptide 9 antibody, cytochrome P450, family 94, subfamily B, polypeptide 2 antibody, cytochrome P450, family 705, subfamily A, polypeptide 22 antibody, cytochrome P450, family 705, subfamily A, polypeptide 23 antibody, cytochrome P450, family 705, subfamily A, polypeptide 30 antibody, cytochrome P450, family 82, subfamily G, polypeptide 1 antibody, cytochrome P450, family 86, subfamily C, polypeptide 2 antibody, cytochrome P450, family 94, subfamily B, polypeptide 3 antibody, cytochrome P450, family 76, subfamily G, polypeptide 1 antibody, cytochrome P450, family 94, subfamily D, polypeptide 2 antibody, cytochrome P450, family 706, subfamily A, polypeptide 4 antibody, cytochrome P450, family 83, subfamily A, polypeptide 1 antibody, cytochrome P450, family 702, subfamily A, polypeptide 2 antibody, cytochrome P450, family 702, subfamily A, polypeptide 3 antibody, cytochrome P450, family 705, subfamily A, polypeptide 2 antibody, cytochrome P450, family 705, subfamily A, polypeptide 3 antibody, cytochrome P450, family 21, subfamily a, polypeptide 1 antibody, cytochrome P450, family 2, subfamily g, polypeptide 1 antibody, vitamin D3 25-Hydroxylase antibody, cytochrome P-450 antibody, cytochrome P450 antibody, olfactory receptor 1440-like antibody, CYP4F3 antibody, Cyp6t1 antibody, CYP705A9 antibody, CYP71A13 antibody, CYP710A2 antibody, UNE9 antibody, CYP705A15 antibody, CYP705A18 antibody, CYP71A20 antibody, CYP705A1 antibody, CPD antibody, CYP71A18 antibody, CYP86A4 antibody, CYP82F1 antibody, CYP711A1 antibody, CYP94C1 antibody, CYP710A1 antibody, CYP98A3 antibody, CYP712A1 antibody, CYP704A1 antibody, CYP704A2 antibody, CYP86A8 antibody, CYP709B2 antibody, CYP709B1 antibody, CYP89A9 antibody, CYP94B2 antibody, CYP705A22 antibody, CYP705A23 antibody, CYP705A30 antibody, CYP82G1 antibody, CYP86C2 antibody, CYP94B3 antibody, CYP76G1 antibody, CYP94D2 antibody, CYP706A4 antibody, CYP83A1 antibody, CYP702A2 antibody, CYP702A3 antibody, CYP705A2 antibody, CYP705A3 antibody, Cyp21a1 antibody, Cyp2g1 antibody, CYP2D25 antibody, LOC100328948 antibody, CYP1A1 antibody, Cyp3a15 antibody, LOC100068520 antibody

Background:

Synonyms: Rabbit Anti-Cytochrome p450 Antibody, Rabbit Anti-CYP1A1 Antibody, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1

Background: Cytochrome p450 belongs to an enzyme superfamily that catalyzes many reactions such as the synthesis of cholesterol, lipids, steroids by oxidizing the compounds and plays a role in drug metabolism. The protein has been known to be stimulated by cigarette smoke. On-going studies link the cytochrome p450 protein with lung cancer. In the liver microsome, it is part of the NADPH-dependent electron transport pathway. The protein has been found expressed in the lung, lymphocytes and placenta. Anti-Cytochrome p450 antibody is useful for researchers interested in cancer research and enzyme research.

Gene Name: CYP1A1

Gene ID: 1543

NCBI Accession: NP_000490

UniProt: P04798

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process