TRPC5 antibody (C-Term)

Catalog No. ABIN6658094

Product Details anti-TRPC5 Antibody

Target: TRPC5 (Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5))

Binding Specificity: C-Term

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRPC5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Anti-TrpC5 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with TrpC5 from human, mouse, and rat based on 100% homology with the immunizing sequence. Cross-reactivity with TrpC5 from other sources has not been determined. Ion Channels research.

Immunogen:

Immunogen: TrpC5 Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to a near c-terminus region of rat TrpC5 (also known as short transient receptor potential channel 5, and Htrp5).

Immunogen Type: Peptide

Clone: S67-15

Isotype: IgG2b

Application Details

Application Notes:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-TrpC5 Antibody is suitable for use in WB, IHC and IP. Expect a band approximately ~110 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Western Blot Dilution: 1 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Storage: RT,4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Target Details for TRPC5

Target: TRPC5 (Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5))

Alternative Name: TrpC5 (TRPC5 Products)

Synonyms: trpc5 antibody, wu:fi73f08 antibody, TRPC5 antibody, Trpc5 antibody, TRP5 antibody, CCE2 antibody, TRP-5 antibody, Trrp5 antibody, trp antibody, transient receptor potential cation channel, subfamily C, member 5a antibody, transient receptor potential cation channel subfamily C member 5 antibody, transient receptor potential cation channel, subfamily C, member 5 antibody, trpc5a antibody, TRPC5 antibody, Trpc5 antibody

Background:

Synonyms: Htrp5, Short transient receptor potential channel 5, TRP5, ansient receptor protein 5

Background: Transient receptor potential cation channel, subfamily C, member 5, also known as TRPC5, is a subtype of the TRPC family of mammalian transient receptor potential ion channels. Homomultimeric TRPC5 and heteromultimeric TRPC5-TRPC1 channels are activated by extracellular reduced thioredoxin. This activation probably plays a role in rheumatoid arthritis. It has also been recently found to be involved in the action on anaesthetics such as choloform, halothane and propofol.

Gene Name: TRPC5

Gene ID: 7224

NCBI Accession: NP_036603

UniProt: Q9UL62