Tamalin/GRASP antibody (C-Term)

Catalog No. ABIN6658234

Product Details anti-Tamalin/GRASP Antibody

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Binding Specificity: C-Term

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tamalin/GRASP antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Cross reactivity with GRASP from other species has not been determined.

Purification: Anti-GRASP Antibody is directed against rat GRASP protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Expect reactivity with the following species based on sequence homology: bovine, canine, human, rat, and mouse.

Immunogen:

Immunogen: Anti-GRASP Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region.

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-GRASP (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 95 kDa in size corresponding to GRASP protein in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Target Details for Tamalin/GRASP

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Alternative Name: GRASP (GRASP Products)

Synonyms: GRASP antibody, tamalin antibody, TAMALIN antibody, general receptor for phosphoinositides 1 associated scaffold protein antibody, GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein antibody, GRASP antibody, grasp antibody, Grasp antibody

Background:

Synonyms: GRIP1-associated protein 1, Glutamate receptor-interacting protein 1, GRASP1

Background: GRASP Antibody detects GRASP protein. PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity. Therefore, GRASP antibody is ideal for investigators involved in neuronal plasticity and remodelling and more generally in Neuroscience.

Gene Name: GRIPAP1

Gene ID: 116493

UniProt: P97879