TSG101 antibody (Tumor Susceptibility Gene 101)

Details for Product anti-TSG101 Antibody No. ABIN6674283
Antigen
  • CG9712
  • DmTSG101
  • Dmel\\CG9712
  • ESCRT-I
  • Tsg101
  • burs
  • dTSg101
  • dTsg101
  • dVps23
  • ept
  • tsg101
  • vps23
  • TSG101
  • MGC76193
  • TSG10
  • VPS23
  • AI255943
  • CC2
  • Rw
  • zgc:86926
  • tumor susceptibility 101
  • Tumor susceptibility gene 101
  • Tumor Susceptibility Gene homolog
  • tumor susceptibility gene 101
  • tumor susceptibility 101a
  • tumor susceptibility 101 L homeolog
  • TSG101
  • tsg-101
  • tsg101
  • Tsg101
  • tsg101a
  • tsg101.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
131
62
52
12
10
8
8
8
6
5
5
4
3
2
1
1
Host
Rabbit
119
16
Clonality
Polyclonal
Conjugate
This TSG101 antibody is un-conjugated
8
5
4
4
4
4
3
3
3
3
3
3
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
110
62
52
19
17
14
6
5
3
3
3
2
1
1
1
Options
Immunogen Fusion protein of human TSG101
Isotype IgG
Purification Affinity purification
Plasmids, Primers & others Plasmids, Primers & others TSG101 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TSG101 (TSG101 Antibody Abstract)
Background The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
Synonyms: TSG10, VPS23
Gene ID 7251
UniProt Q99816
Application Notes Recommended dilutions: WB: 1:500-1:1000, IHC: 1:50-1:100, IF: 1:20-1:50
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C,-80 °C
Storage Comment

Storage: -20 °C/-80 °C

Supplier Images
Image no. 1 for anti-Tumor Susceptibility Gene 101 (TSG101) antibody (ABIN6674283) Western blot analysis of extracts of Hela cell line, using TSG101 antibody.
Image no. 2 for anti-Tumor Susceptibility Gene 101 (TSG101) antibody (ABIN6674283) Western blot analysis of extracts of Hela cell line, using TSG101 antibody.
Product cited in: Zhao, Wu, Duan, Ma, Shen, Wei, Cui, Zhang, Xie, Liu: "Quantitative proteomic analysis of exosome protein content changes induced by hepatitis B virus in Huh-7 cells using SILAC labeling and LC-MS/MS." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5391-402, 2015 (PubMed). Method employed by authors: Western Blotting (WB)

Yu, Yan, Yang, Wu, Ling, Chen, Tang, Tan, Cao, Wu, Yan, Wang: "Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein." in: Nature communications, Vol. 5, pp. 5256, 2014 (PubMed). Method employed by authors: Western Blotting (WB)

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