TNFRSF18 antibody (Tumor Necrosis Factor Receptor Superfamily, Member 18) (C-Term) (Atto 700)

Details for Product anti-TNFRSF18 Antibody No. ABIN6698705
Antigen
  • GITR
  • TNFRSF18
  • AITR
  • Gitr
  • CD357
  • GITR-D
  • TNF receptor superfamily member 18
  • tumor necrosis factor receptor superfamily, member 18
  • TNFRSF18
  • Tnfrsf18
Epitope
C-Term
28
15
15
10
8
3
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
127
119
17
Host
Mouse
86
78
39
Clonality (Clone)
Monoclonal ()
Conjugate
This TNFRSF18 antibody is conjugated to Atto 700
16
13
12
11
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
107
82
79
35
13
12
9
6
3
3
2
2
2
1
Options
Immunogen Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18
Clone T9P4G4-D7
Isotype IgG2b
Specificity Detects 25 kDa.
Purification Protein G Purified
Plasmids, Primers & others Plasmids, Primers & others TNFRSF18 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TNFRSF18 (TNFRSF18 Antibody Abstract)
Background TNFRSF18 is a member of the tumor necrosis factor receptor (TNF-R) superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25+/CD4+ regulatory T cells (1), and could be a suitable molecular target for preventing or treating automimmune diseases (2).
Gene ID 8784
NCBI Accession NP_004186
Pathways Cancer Immune Checkpoints
Application Notes
  • WB (1:1000)
  • optimal dilutions for assays should be determined by the user.
Comment

A 1:1000 dilution of ABIN6698705 was sufficient for detection of Tumor Necrosis Factor Receptor Superfamily, Member 18 in 15 μg of Mouse Skeletal Muscle by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.09 % Sodium Azide
Storage -20 °C
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