TNFRSF18 antibody (C-Term) (Biotin)
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- Target See all TNFRSF18 Antibodies
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNFRSF18 antibody is conjugated to Biotin
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.,Detects 25 kDa.
- Cross-Reactivity
- Human, Mouse
- Purification
- Protein G Purified
- Immunogen
- Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18
- Clone
- T9P4G4-D7
- Isotype
- IgG2b
- Top Product
- Discover our top product TNFRSF18 Primary Antibody
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- Application Notes
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- Comment
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A 1:1000 dilution of ABIN6698707 was sufficient for detection of Tumor Necrosis Factor Receptor Superfamily, Member 18 in 15 μg of Mouse Skeletal Muscle by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- Alternative Name
- TNFRSF18 (TNFRSF18 Products)
- Synonyms
- GITR antibody, TNFRSF18 antibody, AITR antibody, Gitr antibody, CD357 antibody, GITR-D antibody, TNF receptor superfamily member 18 antibody, tumor necrosis factor receptor superfamily, member 18 antibody, TNFRSF18 antibody, Tnfrsf18 antibody
- Background
- TNFRSF18 is a member of the tumor necrosis factor receptor (TNF-R) superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25+/CD4+ regulatory T cells (1), and could be a suitable molecular target for preventing or treating automimmune diseases (2).
- Gene ID
- 8784
- NCBI Accession
- NP_004186
- Pathways
- Cancer Immune Checkpoints
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