VWF antibody (AA 701-800)

Catalog No. ABIN670506

Product Details anti-VWF Antibody

Target: VWF (Von Willebrand Factor (VWF))

Binding Specificity: AA 701-800

Reactivity: Human, Rat, Mouse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VWF antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Predicted Reactivity: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VWF

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-VWF antibody (ABIN670506)

Hsu, Roan, Wang, Huang, Shih, Chen, Wu, Lam: "Hemodynamic, biological, and right ventricular functional changes following intraatrial shunt repair in patients with flow-induced pulmonary hypertension." in: Congenital heart disease, Vol. 12, Issue 4, pp. 533-539, (2017) (PubMed).

Du, Wang, Zhao, Li, Kong, Yang, Zhang: "Gradient nanofibrous chitosan/poly ?-caprolactone scaffolds as extracellular microenvironments for vascular tissue engineering." in: Biomaterials, Vol. 33, Issue 3, pp. 762-70, (2011) (PubMed).

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: VWF (VWF Products)

Synonyms: VWF antibody, si:ch1073-474e24.1 antibody, F8VWF antibody, VWD antibody, 6820430P06Rik antibody, AI551257 antibody, B130011O06Rik antibody, C630030D09 antibody, von Willebrand factor antibody, Von Willebrand factor antibody, VWF antibody, vwf antibody, Vwf antibody

Background:

Synonyms: VWD, F8VWF, von Willebrand factor, vWF

Background: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

Gene ID: 7450

UniProt: P04275