COX15 antibody (Cytochrome C Oxidase Assembly Homolog 15 (Yeast))

Details for Product anti-COX15 Antibody No. ABIN6710886
Antigen
  • COX15
  • wu:fa18g06
  • zgc:56240
  • zgc:77422
  • 2900026G05Rik
  • CEMCOX2
  • COX15, cytochrome c oxidase assembly homolog
  • COX15 homolog, cytochrome c oxidase assembly protein (yeast)
  • COX15 cytochrome c oxidase assembly homolog
  • cytochrome c oxidase assembly homolog 15 (yeast)
  • cytochrome c oxidase assembly protein 15
  • cytochrome c oxidase assembly protein COX15 homolog
  • COX15
  • Cox15
  • cox15
  • LOC100410987
  • LOC100599631
Reactivity
Human, Mouse (Murine), Rat (Rattus)
40
18
17
2
2
2
1
1
1
1
1
Host
Rabbit
36
4
Clonality
Polyclonal
Conjugate
This COX15 antibody is un-conjugated
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
26
23
14
5
1
Options
Immunogen A synthetic peptide corresponding to residues in Human COX15.
Specificity COX15 polyclonal antibody detects endogenous levels of COX15 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity > 95% (by SDS-PAGE)
Plasmids, Primers & others Plasmids, Primers & others COX15 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name COX15 (COX15 Antibody Abstract)
Background The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family. Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues containing high rates of oxidative phosphorylation including brain, heart and muscle. COX15 defects are the cause of a neurodegenerative disorder known as Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).
Molecular Weight ~ 44 kDa
UniProt Q7KZN9
Application Notes WB: 1:500~1:1000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 1 mg/mL in Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term.
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