Nucleolar Protein with MIF4G Domain 1 (NOM1) antibody

Details for Product No. ABIN6710941
Antigen
Reactivity
Human, Rat (Rattus)
16
13
2
Host
Rabbit
16
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
Western Blotting (WB)
8
7
5
3
1
Options
Immunogen A synthetic peptide corresponding to residues in Human NOM1.
Specificity NOM1 polyclonal antibody detects endogenous levels of NOM1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity > 95% (by SDS-PAGE)
Antigen
Alternative Name NOM1 (NOM1 Antibody Abstract)
Background NOM1 (nucleolar protein with MIF4G domain 1), also known as SGD1, is an 860 amino acid protein that localizes to the nucleolus, where it plays a role in targeting PP1. A member of the CWC22 family, NOM1 is expressed in skeletal muscle and heart, and contains one MI domain and a MIF4G domain. The MIF4G typically functions in protein translation and may act as a binding site for members of the eIF4A family. As such, NOM1 is thought to interact with eIF4AI, eIF4AII and eIF4AIII. The gene encoding NOM1 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Molecular Weight ~ 96 kDa
UniProt Q5C9Z4
Application Notes WB: 1:500~1:1000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 1 mg/mL in Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term.