Fibronectin 1 antibody (FN1) (AA 2331-2380)

Details for Product anti-FN1 Antibody No. ABIN6712162
Antigen
  • FN1
  • FN
  • cig
  • fibronectin
  • finc
  • lets
  • msf
  • Fn
  • fn2
  • fb80d10
  • wu:fb80d10
  • CIG
  • ED-B
  • FINC
  • FNZ
  • GFND
  • GFND2
  • LETS
  • MSF
  • E330027I09
  • Fn-1
  • FIBNEC
  • fn-1
  • fibronectin 1
  • fibronectin 1a
  • fibronectin 1 S homeolog
  • FN1
  • fn1
  • fn1a
  • Fn1
  • fn1.S
Alternatives
anti-Human Fibronectin 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 2331-2380
10
6
4
3
3
3
3
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
170
50
33
9
8
7
7
6
4
4
3
1
1
1
Host
Rabbit
110
75
4
3
2
Clonality
Polyclonal
Conjugate
This Fibronectin 1 antibody is un-conjugated
19
13
4
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
135
85
68
37
24
20
18
15
7
2
2
1
1
1
1
Options
Immunogen Synthetic peptide, corresponding to amino acids 2331-2380 of Human Fibronectin 1.
Specificity Fibronectin 1 (F2372) polyclonal antibody detects endogenous levels of Fibronectin 1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity > 95% (by SDS-PAGE)
Plasmids, Primers & others Plasmids, Primers & others Fibronectin 1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Fibronectin 1 (FN1 Antibody Abstract)
Background Fibronectin is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. They occur as dimers of two 200 kDa subunits. They have binding domains for bacterial proteins, collagens, heparin-like molecules and fibrin. Cellular fibronectin is widely distributed in the stroma of malignant tumours.
Molecular Weight ~ 260 kDa
UniProt P02751
Pathways Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy
Application Notes WB: 1:500~1:1000 IHC: 1:50~1:200
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 1 mg/mL in Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term.
Product cited in: Hu, Yang, Hou, Zhang, Zeng, Zhao, Yu, Tang, Tu, Cui, Liu: "LncRNA expression signatures of twist-induced epithelial-to-mesenchymal transition in MCF10A cells." in: Cellular signalling, Vol. 26, Issue 1, pp. 83-93, 2014 (PubMed).

Huang, Yeh, Lin, Yang, Ko, Lin: "Development of fibroblast culture in three-dimensional activated carbon fiber-based scaffold for wound healing." in: Journal of materials science. Materials in medicine, Vol. 23, Issue 6, pp. 1465-78, 2012 (PubMed).

Zhao, Nie, Lv, He, Wang, Hou: "ERβ-mediated estradiol enhances epithelial mesenchymal transition of lung adenocarcinoma through increasing transcription of midkine." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 8, pp. 1304-15, 2012 (PubMed).

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