Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1) antibody

Details for Product No. ABIN6715171
Antigen
Reactivity
Human
47
10
7
4
1
Host
Rabbit
29
29
1
Clonality
Polyclonal
Conjugate
Un-conjugated
14
2
2
2
2
2
1
1
1
1
1
1
Application
Western Blotting (WB)
43
40
8
5
4
4
4
2
1
1
1
1
Options
Immunogen Recombinant protein of human CCL3L1.
Specificity CCL3L1 polyclonal antibody detects endogenous levels of CCL3L1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity > 95% (by SDS-PAGE)
Antigen
Alternative Name CCL3L1 (CCL3L1 Antibody Abstract)
Background This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants.
Molecular Weight ~ 10 kDa
UniProt P16619
Pathways Cellular Response to Molecule of Bacterial Origin
Application Notes WB 1:200 - 1:500
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 1 mg/mL in PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term.
Supplier Images
Image no. 1 for anti-Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1) antibody (ABIN6715171) Western blot analysis of extracts of B cells, using CCL3L1 antibody.