SETD2 antibody (SET Domain Containing 2)

Details for Product anti-SETD2 Antibody No. ABIN6717762
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
75
18
15
3
2
2
Host
Rabbit
62
9
7
Clonality
Polyclonal
Conjugate
This SETD2 antibody is un-conjugated
6
4
4
4
4
4
2
2
2
2
2
2
Application
Western Blotting (WB)
41
39
38
16
6
4
3
2
1
1
Options
Immunogen Recombinant full length Human SETD2.
Specificity SETD2 polyclonal antibody detects endogenous levels of SETD2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity > 95% (by SDS-PAGE)
Antigen
Alternative Name SETD2 (SETD2 Antibody Abstract)
Background Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Molecular Weight ~288 kDa
UniProt Q9BYW2
Pathways Tube Formation
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 1 mg/mL in PBS with 0.1 %  Sodium Azide, 50 % Glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term.
Supplier Images
Image no. 1 for anti-SET Domain Containing 2 (SETD2) antibody (ABIN6717762) Western blot analysis of SETD2 polyclonal antibody