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MADCAM1 antibody

MADCAM1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6719343
  • Target See all MADCAM1 Antibodies
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    Reactivity
    • 45
    • 42
    • 7
    • 1
    Human
    Host
    • 47
    • 15
    • 3
    Rabbit
    Clonality
    • 47
    • 18
    Polyclonal
    Conjugate
    • 23
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MADCAM1 antibody is un-conjugated
    Application
    • 56
    • 31
    • 26
    • 26
    • 16
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for MAdCAM1 detection. Tested with WB in Human.
    Sequence
    QELEGAQALG PEVQEEEEEP QGDEDVLFRV TERWRL
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for MAdCAM1 detection. Tested with WB in Human.
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence of human MAdCAM1 (QELEGAQALGPEVQEEEEEPQGDEDVLFRVTERWRL).
    Isotype
    IgG
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  • Application Notes

    Application details: Western blot|0.1-0.5 μg/mL

    Comment

    Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    Alternative Name
    MADCAM1 (MADCAM1 Products)
    Synonyms
    MACAM1 antibody, AV211525 antibody, mucosal vascular addressin cell adhesion molecule 1 antibody, MADCAM1 antibody, Madcam1 antibody
    Background

    Synonyms: Mucosal addressin cell adhesion molecule 1, MAdCAM-1, hMAdCAM-1, MADCAM1

    Background: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1), also known as MACAM1, is a protein that in humans is encoded by the MADCAM1 gene. By PCR-based analysis of somatic cell hybrids, this gene is mapped to chromosome 19. The protein encoded by this gene is an endothelil cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4 / beta7), L-selectin, and VLA-4 (alpha4 / beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin superfamily and is similar to ICAM-1 and VCAM-1.

    Gene ID
    8174
    UniProt
    Q13477
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