CLPX antibody (AA 337-574)

Catalog No. ABIN7354570

Product Details anti-CLPX Antibody

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Binding Specificity: AA 337-574

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLPX antibody is un-conjugated

Application: Flow Cytometry (FACS)

Purpose: Rabbit IgG Polyclonal Anti-Human CLPX Antibody DyLight® 550 Conjugated, Flow Validated.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG Polyclonal Anti-Human CLPX Antibody DyLight® 550 Conjugated, Flow Validated.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human CLPX recombinant protein (Position: A337-E574).

Isotype: IgG

Application Details

Application Notes:

Application details: Flow Cytometry|1-3 μg/1x106 cells

Comment:

Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: At 2-8°C for one year. Protect from light. Do not freeze.

Target Details for CLPX

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Alternative Name: CLPX (CLPX Products)

Synonyms: AU014732 antibody, E330029I21 antibody, caseinolytic mitochondrial matrix peptidase chaperone subunit antibody, Clpx antibody, CLPX antibody

Background:

Synonyms: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, CLPX

Background: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease. The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

Gene ID: 10845

UniProt: O76031