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Neuropilin 1 antibody (AA 851-923)

NRP1 Reactivity: Human, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN671991
  • Target See all Neuropilin 1 (NRP1) Antibodies
    Neuropilin 1 (NRP1)
    Binding Specificity
    • 14
    • 10
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 851-923
    Reactivity
    • 104
    • 58
    • 49
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 104
    • 24
    • 4
    • 2
    Rabbit
    Clonality
    • 98
    • 36
    Polyclonal
    Conjugate
    • 56
    • 21
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neuropilin 1 antibody is un-conjugated
    Application
    • 99
    • 44
    • 37
    • 27
    • 17
    • 14
    • 13
    • 11
    • 10
    • 8
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Sheep,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human neuropilin-1
    Isotype
    IgG
    Top Product
    Discover our top product NRP1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    Neuropilin 1 (NRP1)
    Alternative Name
    Neuropilin 1 (NRP1 Products)
    Synonyms
    NRP1 antibody, cd304 antibody, neuropilin antibody, np-1 antibody, npn-1 antibody, nrp antibody, nrp-1 antibody, vegf165r antibody, BDCA4 antibody, CD304 antibody, NP1 antibody, NRP antibody, VEGF165R antibody, C530029I03 antibody, NP-1 antibody, NPN-1 antibody, Npn1 antibody, Nrp antibody, neuropilin 1 antibody, neuropilin 1 L homeolog antibody, NRP1 antibody, nrp1 antibody, Nrp1 antibody, nrp1.L antibody
    Background

    Synonyms: NP1, NRP, BDCA4, CD304, VEGF165R, Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, NRP1

    Background: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

    Gene ID
    8829
    UniProt
    O14786
    Pathways
    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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