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RSV-F antibody Primary Antibody

Reactivity: Human BR, ELISA, FACS, IP, WB Host: Mouse Monoclonal Palivizumab unconjugated
Catalog No. ABIN6730990
$360.00
Plus shipping costs $45.00
100 μL
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Delivery in 7 to 8 Business Days
  • Target
    Antibody Type
    Recombinant Antibody
    Reactivity
    Human
    Host
    Mouse
    Clonality
    Monoclonal
    Application
    Blocking Reagent (BR), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
    Purpose
    Palivizumab is a humanised IgG1monoclonal antibody directed to an epitope in the A antigenic site of the fusion protein of respiratory syncytial virus (RSV).
    Specificity
    "Palivizumab is a humanised IgG1monoclonal antibody directed to an epitope in the A antigenic site of the fusion protein of respiratory syncytial virus (RSV)."
    Characteristics
    "This is a therapeutic antibody derived from Synagis and designed for research purposes.Palivizumab, the active ingredient of Synagis, is a humanised IgG1 monoclonal antibody directed to an epitope in the A antigenic site of the fusion protein of respiratory syncytial virus (RSV)." Palivizumab is a humanised IgG1κ monoclonal antibody directed to an epitope in the A antigenic site of the fusion protein of respiratory syncytial virus (RSV). This humanised monoclonal antibody is composed of human (95%) and murine (5%) antibody sequences. It has potent neutralising and fusion-inhibitory activity against both RSV subtype A and B strains.
    Palivizumab serum concentrations of approximately 30 μg/ml have been shown to produce a 99% reduction in pulmonary RSV replication in the cotton rat model.
    Purification
    The commercial therapeutic mAb was diluted with sterile PBS to a final 1 mg/ml.  (original drug Synagis 100 was diluted 1:100)
    Sterility
    Sterile
    Clone
    Palivizumab
  • Application Notes
    Optimal dilution for a specific application should be determined by user
    Comment

    Palivizumab is a recombinant humanised monoclonal antibody produced by DNA technology in mouse myeloma host cells.

    Protocol
    Research-relevant quantities are available as licence-free consumable as diluted variant. Therapeutic monoclonal antibodies can be used from researchers in in vitro and in vivo experiments.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    The dilutant is sterile PBS pH 7.4. No preservatives added
    Preservative
    Without preservative
    Handling Advice
    open only under sterile conditions
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
    Expiry Date
    48 months
  • Target
    Alternative Name
    RSV protein F
    Molecular Weight
    64 kDa
    Gene ID
    1494475
    NCBI Accession
    NC_001781
    UniProt
    O36634
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