ODC1 antibody (AA 321-461)

Catalog No. ABIN674559

Product Details anti-ODC1 Antibody

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Binding Specificity: AA 321-461

Reactivity: Human, Rat, Mouse, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ODC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Dog, Human, Mouse, Pig, Rat

Predicted Reactivity: Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ODC1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ODC1 antibody (ABIN674559)

Chen, Liu, Wang, Wang, Li, Shi, Zhu, Zhang, Pi, Hu, Lin, Odle: "Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge." in: Innate immunity, Vol. 22, Issue 8, pp. 577-587, (2016) (PubMed).

Rossi, Cerquetella, Pengo, Mari, Balint, Bassotti, Manolescu: "Immunohistochemical expression of ornithine decarboxylase, diamine oxidase, putrescine, and spermine in normal canine enterocolic mucosa, in chronic colitis, and in colorectal cancer." in: BioMed research international, Vol. 2015, pp. 172756, (2016) (PubMed).

Target Details for ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Alternative Name: ODC (ODC1 Products)

Background:

Synonyms: ODC, ODC1, Mitochondrial 2-oxodicarboxylate carrier, Solute carrier family 25 member 21, SLC25A21

Background: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.

Gene ID: 89874

UniProt: P11926