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SFRP1 antibody (AA 201-314)

SFRP1 Reactivity: Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN674694
  • Target See all SFRP1 Antibodies
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Binding Specificity
    • 14
    • 11
    • 8
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-314
    Reactivity
    • 61
    • 47
    • 39
    • 3
    • 2
    • 2
    • 1
    • 1
    Mouse, Rat
    Host
    • 75
    • 9
    • 2
    • 2
    Rabbit
    Clonality
    • 77
    • 11
    Polyclonal
    Conjugate
    • 28
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SFRP1 antibody is un-conjugated
    Application
    • 66
    • 32
    • 30
    • 12
    • 12
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SFRP1
    Isotype
    IgG
    Top Product
    Discover our top product SFRP1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Wang, Xie, Xie, Wan, Ma, Qi, Yang: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." in: Neuroreport, Vol. 26, Issue 12, pp. 695-702, (2015) (PubMed).

  • Target
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Alternative Name
    SFRP1 (SFRP1 Products)
    Synonyms
    FRP antibody, FRP-1 antibody, FRP1 antibody, FrzA antibody, SARP2 antibody, 2210415K03Rik antibody, AW011917 antibody, AW107218 antibody, AW742929 antibody, sFRP-1 antibody, CSFRP1 antibody, SFRP1 antibody, XfrzA antibody, frp antibody, frp-1 antibody, frp1 antibody, frzA antibody, sarp2 antibody, sfrp1 antibody, LOC100231868 antibody, Srfp1a antibody, wu:fd19b09 antibody, secreted frizzled related protein 1 antibody, secreted frizzled-related protein 1 antibody, Secreted frizzled-related protein 1 antibody, secreted frizzled-related protein 1a antibody, secreted frizzled-related protein 1b antibody, SFRP1 antibody, Sfrp1 antibody, sfrp1 antibody, sfrp1a antibody, sfrp1b antibody
    Background

    Synonyms: FRP, FRP1, FrzA, FRP-1, SARP2, Secreted frizzled-related protein 1, sFRP-1, Secreted apoptosis-related protein 2, SARP-2, SFRP1

    Background: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

    Gene ID
    6422
    UniProt
    Q8N474
    Pathways
    WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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