LRRC4 antibody (AA 501-600)

Catalog No. ABIN676148

Product Details anti-LRRC4 Antibody

Target: LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))

Binding Specificity: AA 501-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRRC4

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LRRC4

Target: LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))

Alternative Name: LRRC4 (LRRC4 Products)

Synonyms: NGL-2 antibody, MBAG1 antibody, NLG-2 antibody, Nag14 antibody, leucine rich repeat containing 4 antibody, LRRC4 antibody, Lrrc4 antibody

Background:

Synonyms: BAG, Brain tumor associated protein LRRC4, Brain tumor-associated protein BAG,Leucine rich repeat containing 4, Leucine rich repeat containing protein 4,Leucine-rich repeat-containing protein 4, Lrrc4, LRRC4_HUMAN, MGC133342, MGC133343, NAG14, Nasopharyngeal carcinoma associated gene 14 protein,Nasopharyngeal carcinoma-associated gene 14 protein, Netrin G2 ligand,Netrin-G2 ligand, NGL 2, NGL2, NGL-2, OTTHUMP00000212282, OTTHUMP00000212283,OTTHUMP00000212284.

Background: This gene is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown. Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitement of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma.

Gene ID: 64101

Pathways: Synaptic Membrane