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Integrin beta 5 antibody (ITGB5) (AA 701-799) (HRP) Primary Antibody

ITGB5 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN677477
$442.20
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target
    Integrin beta 5 (ITGB5)
    Binding Specificity
    • 10
    • 10
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-799
    Reactivity
    • 68
    • 30
    • 24
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 57
    • 7
    • 3
    • 2
    Rabbit
    Clonality
    • 68
    • 1
    Polyclonal
    Conjugate
    • 32
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 5 antibody is conjugated to HRP
    Application
    • 51
    • 38
    • 20
    • 12
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Cow, Human, Mouse, Pig, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Integrin beta 5
    Isotype
    IgG
  • Application Notes
    ELISA 1:500-1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
    Preservative
    Gentamicin sulfate
    Precaution of Use
    This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4 °C
    Expiry Date
    12 months
  • Target
    Integrin beta 5 (ITGB5)
    Alternative Name
    Integrin beta 5 (ITGB5 Antibody Abstract)
    Synonyms
    ITGB5, AA475909, AI874634, ESTM23, [b]-5, [b]5, [b]5A, [b]5B, beta-5, beta5, RGD1563276, integrin, beta 5, integrin beta 5, integrin subunit beta 5, ITGB5, Itgb5
    Background

    Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function.The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer. This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated. This integrin is found in a variety of cells in most normal tissue.

    Subcellular location: Cell membrane, Extracellular matrix

    Synonyms: Integrin beta 5, Integrin beta-5, integrin, beta 5, ITB5_HUMAN, Itgb5, AA475909, AI874634, beta-5, beta5, ESTM23, [b]-5, [b]5, [b]5A, [b]5B FLJ26658, ITGB 5, ITGB5, Integrin _5.

    Gene ID
    3693
    UniProt
    P18084
    Pathways
    Integrin Complex
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