HSD3B7 antibody (AA 281-369) (Biotin)

Catalog No. ABIN680020

Product Details anti-HSD3B7 Antibody (Biotin)

Target: HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))

Binding Specificity: AA 281-369

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD3B7 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSD3B7

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HSD3B7

Target: HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))

Alternative Name: Hsd3b7 (HSD3B7 Products)

Synonyms: CBAS1 antibody, PFIC4 antibody, SDR11E3 antibody, AI195443 antibody, BB098564 antibody, Cca2 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 antibody, HSD3B7 antibody, Hsd3b7 antibody

Background:

Synonyms: 3 beta-hydroxysteroid dehydrogenase type 7, 3 beta-hydroxysteroid dehydrogenase type VII, 3-beta-HSD VII, 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase, C(27) 3-beta-HSD, Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase, HSD3B7

Background: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis.

Gene ID: 80270

UniProt: Q9H2F3