Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Chromogranin A antibody

CHGA Reactivity: Human WB, IHC (f) Host: Mouse Monoclonal CHGA-777 unconjugated
Catalog No. ABIN6936985
  • Target See all Chromogranin A (CHGA) Antibodies
    Chromogranin A (CHGA)
    Reactivity
    • 198
    • 73
    • 66
    • 28
    • 28
    • 15
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 106
    • 97
    • 5
    • 1
    Mouse
    Clonality
    • 124
    • 84
    Monoclonal
    Conjugate
    • 92
    • 18
    • 11
    • 10
    • 10
    • 10
    • 10
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Chromogranin A antibody is un-conjugated
    Application
    • 113
    • 107
    • 70
    • 65
    • 59
    • 50
    • 32
    • 13
    • 13
    • 11
    • 10
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificity
    Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
    No Cross-Reactivity
    Rat (Rattus)
    Cross-Reactivity (Details)
    Human. Does not react with Rat.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human CHGA protein
    Clone
    CHGA-777
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CHGA Primary Antibody
  • Application Notes

    Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: PC12 cells. Adrenal gland, bowel, thyroid, pancreas or pheochromocytoma.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    Chromogranin A (CHGA)
    Alternative Name
    CHGA (CHGA Products)
    Synonyms
    CGA antibody, CG-ALPHA antibody, FSHA antibody, GPHA1 antibody, GPHa antibody, HCG antibody, LHA antibody, TSHA antibody, ChrA antibody, fj05f09 antibody, si:dkey-177p2.2 antibody, wu:fj05f09 antibody, zgc:101749 antibody, zgc:56075 antibody, CHGA antibody, cgA antibody, chga antibody, chromogranin A antibody, glycoprotein hormones, alpha polypeptide antibody, uncharacterized CHGA antibody, chromogranin A S homeolog antibody, CHGA antibody, CGA antibody, Chga antibody, chga antibody, chga.S antibody
    Background
    Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Pituitary Secretory Protein I, SP-I, Vasostatin I or II,Chromogranin A / CHGA (Neuroendocrine Marker)
    Cellular localisation: Finely granular cytoplasmic
    Molecular Weight
    68-75kDa
    Gene ID
    1113, 150793
    UniProt
    P10645
    Pathways
    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
You are here:
Support