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NADPH Oxidase 4 antibody

NOX4 Reactivity: Human WB, ELISA, Coat Host: Mouse Monoclonal NOX4-1245 unconjugated
Catalog No. ABIN6938080
  • Target See all NADPH Oxidase 4 (NOX4) Antibodies
    NADPH Oxidase 4 (NOX4)
    Reactivity
    • 94
    • 40
    • 36
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 84
    • 15
    Mouse
    Clonality
    • 74
    • 26
    Monoclonal
    Conjugate
    • 36
    • 10
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NADPH Oxidase 4 antibody is un-conjugated
    Application
    • 83
    • 42
    • 41
    • 25
    • 18
    • 14
    • 13
    • 13
    • 9
    • 8
    • 7
    • 3
    • 3
    Western Blotting (WB), ELISA, Coating (Coat)
    Specificity
    The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.
    Cross-Reactivity (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant human NOX4 protein
    Clone
    NOX4-1245
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product NOX4 Primary Antibody
  • Application Notes

    Known_Application: ELISA (For coating, order Ab without BSA)Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: PC-12, JAR cells. Kidney.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    NADPH Oxidase 4 (NOX4)
    Alternative Name
    NOX4 (NOX4 Products)
    Synonyms
    KOX antibody, KOX-1 antibody, RENOX antibody, AI648021 antibody, nox4 antibody, NOX4 antibody, NADPH oxidase 4 antibody, NOX4 antibody, Nox4 antibody, nox4 antibody, PTRG_09562 antibody
    Background
    Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1, NADPH oxidase 4, Nox4, Renal NAD(P)H-oxidase, RENOX,NOX4 / NADPH Oxidase 4
    Cellular localisation: Cytoplasm and Cell Surface
    Molecular Weight
    70kDa
    Gene ID
    50507, 371036
    UniProt
    Q9NPH5
    Pathways
    Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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