Fibronectin 1 antibody
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- Target See all Fibronectin 1 (FN1) Antibodies
- Fibronectin 1 (FN1)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Fibronectin 1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
- Specificity
- Fibronectin is a dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing. This MAb is directed against the peptide core and reacts with both the plasma and cellular forms of fibronectin. It blocks the fibronectin-medicated cell attachment not by disrupting the collagen-fibronectin interaction, but by interfering with the attachment of fibronectin to its receptor on the cell surface.
- Purification
- Purified by Protein A/G
- Immunogen
- Human fibronectin Purified from serum by affinity chromatography on gelatin-sepharose
- Clone
- SPM539
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product FN1 Primary Antibody
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- Application Notes
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Positive Control: SW156 cells. Kidney.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- Fibronectin 1 (FN1)
- Alternative Name
- FN1 (FN1 Products)
- Synonyms
- FN1 antibody, FN antibody, cig antibody, fibronectin antibody, finc antibody, lets antibody, msf antibody, Fn antibody, fn2 antibody, fb80d10 antibody, wu:fb80d10 antibody, CIG antibody, ED-B antibody, FINC antibody, FNZ antibody, GFND antibody, GFND2 antibody, LETS antibody, MSF antibody, E330027I09 antibody, Fn-1 antibody, FIBNEC antibody, fn-1 antibody, fibronectin 1 antibody, fibronectin 1a antibody, fibronectin 1 S homeolog antibody, FN1 antibody, fn1 antibody, fn1a antibody, Fn1 antibody, fn1.S antibody
- Molecular Weight
- 220kDa (monomer), 440kDa (dimer)
- Gene ID
- 2335
- UniProt
- P02751
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy
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